Sponsored by: 

Ken Milne MD, MSc, CCFP-EM. FCFP. FRRMS

Dr. Milne is a staff physician at the Strathroy Middlesex General Hospital in Strathroy, Ontario, Canada. He has been doing medical research for 40 years publishing on a variety of topics. Dr. Milne has been working clinically for 28 years and is an Associate Professor in the Department of Medicine (Division of Emergency Medicine) and Department of Family Medicine at the Schulich School of Medicine and Dentistry. He teaches evidence-based medicine, clinical epidemiology, critical appraisal and biostatistics at Western University in London, Ontario. Dr. Milne is passionate about skepticism and critical thinking. He is the creator of the knowledge translation project, The Skeptics’ Guide to Emergency Medicine (TheSGEM).  Ken is married to Barb and has three amazing children.

Dr. Milne serves as a senior editor of Academic Emergency Medicine. He has no funding from the pharmaceutical or biomedical device industry. He is on faculty for the Center for Medical Education and EMRAP. Dr. Milne does partake in medical malpractice reviews and does hold a patent on a pediatric resuscitation device.

We examine:

2:00 – The importance of primary literature

4:10 – Why?

10:10 – Literature, critically appraising articles, & levels of evidence

13:20 – Evidence Based Medicine

17:30 – Guidelines & Protocols

22:22 – Epinephrine in Cardiac Arrest

• https://thesgem.com/2018/12/sgem238-the-epi-dont-work-for-ohca/
• https://www.nejm.org/doi/full/10.1056/nejmoa040325
• https://www.nejm.org/doi/full/10.1056/nejmoa1806842

28:30 – Sodium Bicarbonate in Cardiac Arrest

• https://thesgem.com/2023/02/sgem394-say-bye-bye-bicarb-for-pediatric-in-hospital-cardiac-arrest/
• https://pubmed.ncbi.nlm.nih.gov/35880872/

32:10 – Advanced Airways

• https://thesgem.com/2019/03/sgem247-supraglottic-airways-gonna-save-you-for-an-ohca/
• https://pubmed.ncbi.nlm.nih.gov/30167701/

36:10 – “Treat the patient, not the monitor”

42:05 – TTM (Targeted Temperature Management)

• https://thesgem.com/2013/01/sgem21-ice-ice-baby/
• https://thesgem.com/2021/07/sgem336-you-cant-always-get-what-you-want-ttm2-trial/
• http://www.nejm.org/doi/full/10.1056/NEJMoa012689
• https://www.nejm.org/doi/full/10.1056/nejmoa1310519
• https://www.nejm.org/doi/full/10.1056/NEJMoa2100591

48:22 – “Be Skeptical”

• https://onlinelibrary.wiley.com/doi/full/10.1111/acem.14312

51:15 – TBI Management/TXA

• https://thesgem.com/2019/10/sgem270-crash-3-txa-for-traumatic-head-bleeds/
• https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)32233-0/fulltext
• https://caep.ca/periodicals/Volume_22_Issue_3/Vol_22_Issue_3_Page_297_-_298_Blanchard.pdf

61:05 – Final Thoughts

“No statistical difference”

Important/Relevant Articles

https://pubmed.ncbi.nlm.nih.gov/23766747/

https://www.bmj.com/content/312/7023/71

OPALS: https://www.nejm.org/doi/full/10.1056/nejmoa040325

PARAMEDIC 2: https://www.nejm.org/doi/full/10.1056/nejmoa1806842

https://pubmed.ncbi.nlm.nih.gov/35880872/

AIRWAYS 2: https://pubmed.ncbi.nlm.nih.gov/30167701/

http://www.nejm.org/doi/full/10.1056/NEJMoa012689
TTM 1: https://www.nejm.org/doi/full/10.1056/nejmoa1310519

TTM 2: https://www.nejm.org/doi/full/10.1056/NEJMoa2100591

https://onlinelibrary.wiley.com/doi/full/10.1111/acem.14312

CRASH 3: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)32233-0/fulltext